Search results for "Hyperbaric oxygen"
showing 10 items of 13 documents
Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: Insights from the LUNG SAFE study
2020
Abstract Background Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence o…
Induction of heme oxygenase-1 and adaptive protection against the induction of DNA damage after hyperbaric oxygen treatment.
2000
Hyperbaric oxygen (HBO) treatment of human subjects (i.e. exposure to 100% oxygen at a pressure of 2.5 ATA for a total period of 3 x 20 min) caused clear and reproducible DNA damage in lymphocytes, as detected with the comet assay (single cell gel electrophoresis). Induction of DNA damage was found only after the first HBO exposure and not after further treatments of the same individuals. Furthermore, blood taken 24 h after HBO treatment was significantly protected against the induction of DNA damage by hydrogen peroxide (H(2)O(2)) in vitro, indicating that adaptation occurred due to induction of antioxidant defenses. The cells were not significantly protected against the genotoxic effects …
Effect of undersized drilling on the stability of immediate tapered implants in the anterior maxillary sector. A randomized clinical trial.
2020
Background To evaluate the effect of undersized drilling on the primary and secondary stability of immediate implants placed in the anterior maxilla. Material and Methods A comparative randomized clinical trial was carried out in 30 healthy adults. Thirty tapered implants, 16 involving conventional drilling and 14 undersized drilling, were placed immediately after anterior maxillary tooth removal. Insertion torque and implant stability assessed by resonance frequency analysis (RFA) were evaluated at three different timepoints: at implant placement and 6 and 12 weeks post-implantation. The results were compared using parametric statistical tests. Results All implants showed adequate stabilit…
Breathing 100% oxygen during water immersion improves postimmersion cardiovascular responses to orthostatic stress
2016
Abstract Physiological compensation to postural stress is weakened after long‐duration water immersion (WI), thus predisposing individuals to orthostatic intolerance. This study was conducted to compare hemodynamic responses to postural stress following exposure to WI alone (Air WI), hyperbaric oxygen alone in a hyperbaric chamber (O 2 HC), and WI combined with hyperbaric oxygen (O 2 WI), all at a depth of 1.35 ATA, and to determine whether hyperbaric oxygen is protective of orthostatic tolerance. Thirty‐two healthy men underwent up to 15 min of 70° head‐up tilt (HUT) testing before and after a single 6‐h resting exposure to Air WI ( N = 10), O 2 HC ( N = 12), or O 2 WI ( N = 10). Heart …
Modulation of tumor oxygenation
1998
There is a large body of evidence suggesting that deficiencies in the O2 supply of tumors exist due to restrictions (i) in the O2 delivery by perfusion and/or diffusion, and (ii) in the O2 transport capacity. Whereas the former are mostly based on inadequate and heterogeneous microcirculatory functions, the latter are predominantly due to tumor-associated anemia. Possible uses and limitations of measures are discussed which can increase the microvascular O2 content and thus may preferentially serve to enhance diffusion-limited O2 availability. In addition, means are described for improving and increasing the uniformity of microcirculation thus possibly enhancing perfusion-limited O2 deliver…
An Atypical Case of Taravana Syndrome in Mediterraneo
2010
Dysbaric accidents are usually referred to compressed air-supplied diving. Nonetheless, diving accidents are known to have occurred among breath-hold divers also and some cases are reported in medical literature. A male professional breath hold diver (57 year old) presented neurological disorders as dizziness, sensory numbness, blurred vision and left phronto-parietal pain after many dives to a 30-35 meters seawater depth. He went home after the regression of the symptoms and runned 8 Km the following morning. Pain, sensory numbness and dizziness occurred after running. He went by himself to the hospital where he had a grand mal seizure and lost consciousness. A magnetic resonance imaging o…
T helper 1 response is correlated with widespread pain, fatigue, sleeping disorders and the quality of life in patients with fibromyalgia and is modu…
2019
Hyperbaric oxygen therapy (HBOT) has been used as treatment for different clinical conditions, including fibromyalgia (FM). HBOT modulates brain activity, ameliorates chronic pain and modifies the ratio of immune cells. Clinical studies have provided evidence that FM is associated with immune system dysregulation. In the present study we aimed to evaluate the effect of HBOT on immune system and on the quality of life-style of FM patients.Patients with primary FM and controls were treated with HBOT. Physical, emotional and social assessment, quality of sleep, tender points, intensity score, WPI and symptom severity were evaluated before and after HBOT. Furthermore, a characterisation of CD4 …
Inflammatory mediators and other biomarkers in co-intoxicated patients after hyperbaric oxygen therapy (HBO2)
2016
Objective: The present study was conducted in attempt to identify reliable biomarkers in predicting the severity of neurological injury. Materials and methods: A number of 30 patients with confirmed CO poisoning and a number of 7 healthy control volunteers were involved into the study. All participants received at least 60 minutes of hyperbaric oxygen therapy (HBO2) at 2.5 atmospheres absolute (ATA). Standard blood gas analysis was performed on 10 mL venous blood samples obtained immediately before and after HBO2. Seven biomarkers and carboxyhemoglobin (COHb) levels were measured. Results: Following HBO2, all patients recovered fully and were discharged in stable condition. Significant diff…
Effectiveness of Respiratory Hyperoxia, of Normobaric and of Hyperbaric Oxygen Atmospheres in Improving Tumor Oxygenation
1984
A restriction and an inhomogeneous distribution of diffusive and convective oxygen supply is considered the main cause for pronounced radioresistance in solid tumors (Thomlinson and Gray, 1955; Tannock, 1972). One way to alleviate this crucial problem in tumor therapy is the direct enhancement of oxygen delivery to the cancer cells. This can be performed either by the tumor host breathing pure O2 (respiratory hyperoxia, RHO) or by whole body exposure to pure O2 atmospheres at normobaric or hyperbaric pressures (normobaric oxygenation NMO, and hyperbaric oxygenation, HPO, respectively). Numerous investigations have been undertaken both in animals and in man using RHO, NMO, or HPO as an adjuv…
Surgical treatment of pharyngostomes in irradiated patients. Our experience with musculocutaneous pectoralis major flap and hyperbaric oxygen therapy
2005
Surgical treatment of pharyngostomes in irradiated patients. Our experience with musculocutaneous pectoralis major flap and hyperbaric oxygen therapy. Cordova A, Corradino B, Pirrello R, Di Lorenzo S, Dispenza C, Moschella F. Source Dipratimento di Discipline Chirurgiche ed Oncologiche, Divisione di Chirurgia Plastica e Ricostruttiva, Facolta di Medicina, Universita di Palermo, Palermo, Italy. chirplas@unipa.it Abstract CONCLUSION: Our experience confirms that pectoralis major flap is the first-choice technique for repairing recurrent hypopharyngeal fistulae in previously irradiated patients in whom microsurgical techniques are not indicated, and that hyperbaric oxygen therapy helps to solv…